Development of small-lumen vascular prostheses made of bacterial cellulose for cardiac and vascular surgery

ArtiFex Medical GmbH

Vienna (Karl-Farkas-Gasse 22) · ATNew on Amplifa

2020Founded (18.05.2020, Vienna)

Spin-offUniversity Hospital Basel

2–10Employees (LinkedIn specification)

FN 533647aCompany Register, Commercial Court Vienna

About ArtiFex Medical

ArtiFex Medical GmbH is a medical technology company founded in Vienna in 2020 and a spin-off of the University Hospital Basel. The company develops, markets and distributes products related to artificial vascular grafts. At the center is a patented platform for small-diameter vascular grafts based on bacterial cellulose: The natural polymer with a nanofibrillar structure forms a smooth blood-contacting surface and is intended to support tissue integration with a low inflammatory response. A nylon reinforcement layer provides compliance, kink resistance and mechanical stability without synthetic material coming into contact with the blood. Manufacturing is bioreactor-based with controlled regulation of internal diameter, wall structure and mechanical performance. Target applications lie in coronary bypass surgery (CABG) and dialysis access; financing is provided through FFG funding, NLC Health Ventures and private investors.

Site: Vienna
Processes: Bioreactor-based manufacturing of vascular grafts from bacterial cellulose (patented graft platform), Development and marketing of products related to artificial vascular grafts, Development, marketing and distribution of artificial vascular grafts (small-diameter vascular
Materials: Bacterial cellulose, Nylon (reinforcement layer), Bacterial Cellulose, Nylon (Reinforcement Layer)
Founded: 2020
Industries: Medical Technology, Cardiovascular Surgery, Dialysis, Cardiovascular/vascular surgery, Dialysis/CABG

01
Bioreactor-based cultivation of bacterial cellulose
02
Combination with nylon reinforcement layer
03
Characterization (internal diameter, wall structure, mechanical performance)
04
Preclinical and regulatory development
05
Marketing and distribution

Materials & Processes

Bacterial Cellulose

Natural polymer with nanofibrillar structure as the blood-contacting base material of the grafts.

Nylon (Reinforcement Layer)

Provides compliance, kink resistance and mechanical strength without blood contact.

Locations

Vienna

Headquarters, Development and Manufacturing

Materials: Bacterial cellulose, Nylon

Bioreactor (controlled manufacturing: internal diameter, wall structure, mechanical performance)

Products

**Small-diameter vascular graft (bacterial cellulose)**Bioreactor manufacturing · Cardiovascular surgery / dialysis

Inside the production

Reimagining Vascular Grafts Through Nature's Precision

Applications in cardiovascular surgery and dialysis

Industries

Medical TechnologyCardiovascular SurgeryDialysisCardiovascular/vascular surgeryDialysis/CABG

Processes & technical limits

Processes	Tolerance	Max. part	Weight	Lot size	Materials
Bioreactor-based manufacturing of vascular grafts from bacterial cellulose (patented graft platform)Plastics	–	–	–	–	Bacterial cellulose, Nylon
Development and marketing of products related to artificial vascular graftsEngineering	–	–	–	–	Bacterial cellulose

1 Anlagen & Maschinen

Machine	Manufacturer / model	Quantity	Working area	Year built	Site
Bioreactor (controlled manufacturing of the grafts: internal diameter, wall structure, mechanical	–	–	–	–	Vienna

Additional services

Development, marketing and distribution of artificial vascular grafts (small-diameter vascular

History

2020
Foundation of ArtiFex Medical GmbH on 18.05.2020 in Vienna as a spin-off of the University Hospital Basel (FN 533647a)