Development and manufacture of biomaterials for dentistry, oral and maxillofacial medicine
botiss biomaterials GmbH
Hauptstr. 28, 15806 Zossen bei BerlinNew on Amplifa
About botiss biomaterials
botiss biomaterials GmbH is a company founded in 2009 and headquartered in Zossen near Berlin, specializing in dental and tissue regeneration. The product range includes bone substitute materials such as cerabone® (bovine bone mineral, produced in a 1200°C production process), maxgraft® (processed human donor bone, processed by Cells+Tissuebank Austria), the fully synthetic biphasic calcium phosphate maxresorb®, collagen membranes from porcine dermis and pericardium (collprotect®, Jason®), soft tissue substitutes (mucoderm®), wound support products (collacone®, collafleece®), non-resorbable PTFE membranes (permamem®) as well as resorbable magnesium membranes and screws (NOVAMag®) and titanium pins for membrane fixation. The products of the 360° botiss regeneration system are available in over 100 countries worldwide through a global network of distribution partners. According to its own statements, the company invests substantially in research and education, among other things with the botiss academy and the international bone & tissue days.
- Site
- Zossen near Berlin
- Processes
- Manufacture of bone substitute material (cerabone®, 1200°C production process), Allograft processing (maxgraft® granules/blocks), Custom allogeneic bone block (maxgraft® bonebuilder), Synthetic bone substitute material (maxresorb®, biphasic calcium phosphate), Manufacture of collagen membranes (collprotect®, Jason®), Manufacture of non-resorbable membrane (permamem®), Manufacture of magnesium membranes and screws (NOVAMag®), Titanium pin set for membrane fixation
- Materials
- Bovine bone mineral (cerabone®), Human donor bone (maxgraft®), Biphasic calcium phosphate (maxresorb®), Porcine collagen (collprotect®, collacone®, collafleece®, Jason®), PTFE (permamem®), Magnesium (NOVAMag®), Titanium (titan pin set), Hyaluronate (maxgraft® +HyA, cerabone® +HyA)
- Founded
- 2009
- Employees
- 51–200
- Industries
- Dentistry, Oral surgery, Implantology, Medical technology/biomaterials, Biotechnology, Pharmaceutical/biomaterials manufacturing
- 01
Raw material selection (xenograft, allograft, synthetic, collagen)
- 02
Processing and treatment (e.g. 1200°C process, purification process of the
- 03
Product manufacturing (granules, blocks, membranes, cones, screws)
- 04
Quality assurance and clinical validation
- 05
Distribution via a global distribution partner network
Materials and Products
Bovine bone mineral (cerabone®)
Natural bone substitute material, produced in a 1200°C production process.
Human donor bone (maxgraft®)
Allograft material, processed by Cells+Tissuebank Austria in a special purification method.
Biphasic calcium phosphate (maxresorb®)
Fully synthetic bone substitute material with controlled resorption properties.
Porcine collagen (collprotect®, collacone®, collafleece®, Jason®)
Native collagen membranes, cones and sponges made from porcine dermis or pericardium for GBR/GTR and wound management.
PTFE (permamem®)
Particularly thin, non-resorbable, biocompatible barrier membranes.
Magnesium (NOVAMag®)
Fully resorbable, biodegradable metal membranes and fixation screws.
Titanium (titan pin set)
Titanium pins for fixing barrier membranes in GBR/GTR.
Hyaluronate (maxgraft® +HyA, cerabone® +HyA)
Combination of established bone substitute materials with the well-known properties of hyaluronic acid.
Acellular dermal collagen matrix (mucoderm®)
Alternative to autologous soft tissue grafts for various soft tissue indications.
Locations
Zossen near Berlin
DEHeadquarters
Products
Inside the production
Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| Manufacture of bone substitute material (cerabone®, 1200°C production process)Other (medical technology/biomaterials) | – | – | – | – | Bovine bone mineral |
| Allograft processing (maxgraft® granules/blocks)Other (medical technology/biomaterials) | – | – | – | – | Human donor bone |
| Custom allogeneic bone block (maxgraft® bonebuilder)Engineering | – | – | – | – | Human donor bone |
| Synthetic bone substitute material (maxresorb®, biphasic calcium phosphate)Other (medical technology/biomaterials) | – | – | – | – | Calcium phosphate |
| Manufacture of collagen membranes (collprotect®, Jason®)Other (medical technology/biomaterials) | – | – | – | – | Porcine dermis, Porcine pericardium |
| Manufacture of non-resorbable membrane (permamem®)Other (medical technology/biomaterials) | – | – | – | – | PTFE |
| Manufacture of magnesium membranes and screws (NOVAMag®)Joining | – | – | – | – | Magnesium |
| Titanium pin set for membrane fixationJoining | – | – | – | – | Titanium |
| Acellular dermal collagen matrix (mucoderm®)Other (medical technology/biomaterials) | – | – | – | – | Collagen |
| Collagen cones and sponges (collacone®, collafleece®)Other (medical technology/biomaterials) | – | – | – | – | Porcine collagen |
Additional services
History
- 2009
Foundation of botiss biomaterials
- 2021
Launch of a new generation of dental biomaterials (including the HyA product line)