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Develops intraoperative OCT imaging with AI-assisted navigation for neurosurgery

CL

Clee Medical SA

Geneva (Chemin des Mines 9) · SwitzerlandNew on Amplifa

2024Founded
2–10Employees
GenevaLocation
SALegal form

About Clee Medical

Clee Medical SA is a medical technology start-up founded in 2024 and based in Geneva, spun out of the MICA (Minimally Invasive Intracranial Access) research project at the Wyss Center. The company develops an imaging and navigation system based on optical coherence tomography (OCT) for neurosurgery. The system provides real-time images of the brain with a resolution of 15 micrometers – without contrast agents and without radiation – and enables the detection of blood vessels and tissue during the procedure. AI and machine learning methods support navigation. The single-use endoscopy probe is compatible with existing neurosurgical workflows and targets stereotactic and functional procedures such as neuromodulation, biopsies, sEEG and lesioning. The goal is to close the gap between preoperative MRI diagnostics and intraoperative precision.

Site
Geneva
Processes
Development of intraoperative imaging (OCT) with AI-assisted navigation for neurosurgery, Single-use endoscopy probe compatible with existing neurosurgical workflows, Real-time detection of blood vessels and tissue, Ultra-high-resolution imaging (15 micrometers) without contrast agents or radiation
Materials
Optical Coherence Tomography (OCT), Machine Learning / AI Navigation
Certificates
ISO 13485, ISO 9001
Founded
2024
Employees
2–10
Industries
Neurotechnology, Medical technology, Functional neurosurgery, Stereotactic neurosurgery
  1. 01

    Research & Development

  2. 02

    Optics and system design

  3. 03

    Software development (image processing, AI)

  4. 04

    Prototype construction

  5. 05

    Testing & Regulatory

Technology & Processes

OCT

Optical Coherence Tomography (OCT)

Ultra-high-resolution intraoperative imaging with 15 micrometer resolution without contrast agents or radiation.

KI

Machine Learning / AI Navigation

Real-time detection of blood vessels and tissue for safe navigation in the brain.

Location

Geneva

CH

Headquarters, development

Industries

NeurotechnologyMedical technologyFunctional neurosurgeryStereotactic neurosurgery

Additional services

Development of intraoperative imaging (OCT) with AI-assisted navigation for neurosurgerySingle-use endoscopy probe compatible with existing neurosurgical workflowsReal-time detection of blood vessels and tissueUltra-high-resolution imaging (15 micrometers) without contrast agents or radiation

Quality

An in-house quality and regulatory team is preparing the first clinical use (FIH study); certifications have not yet been published.

EvidenceGeneva
ISO 13485
ISO 9001

History

  1. 2024

    Clee Medical officially founded (incorporation October 2024); spin-off from the Wyss Center in Geneva (MICA research project), spun out December 2024

  2. 2025

    First scientific paper “Minimally-invasive common-path OCT system for neurosurgery applications” published in Biomedical Optics Express; first company anniversary

  3. 2025

    Ranked for the first time in the Swiss Top 100 Startups (#56)

  4. 2026

    Seed financing round closed, led by High-Tech Gründerfonds (HTGF) with participation from Zürcher Kantonalbank, Kickfund, FONGIT, Venture Kick and Wyss Geneva; ranked #11 in the Swiss Top 100 Startups; two US patents granted (US 12,733,792 & US 12,727,891)

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