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Vacuum-superinsulated cryogenic vessels, transfer lines and turnkey biobanks for deep-cold liquefied gases.

CR

Cryotherm GmbH & Co. KG

Kirchen (Sieg), Rhineland-PalatinateNew on Amplifa

1964Founded (start of vessel manufacturing, Gewerkschaft
1979Founding of Siegtal Cryotherm GmbH
120–2,400 lVolume range of BIOSAFE® sample storage vessels
down to -269 °COperating temperatures (LHe)

About Cryotherm

Cryotherm GmbH & Co. KG has been manufacturing low-temperature technology for the storage, transport and transfer of deep-cold liquefied gases such as nitrogen, helium, hydrogen, argon, oxygen and LNG for over 50 years. The product range includes vacuum-superinsulated cryogenic and sample storage vessels (including BIOSAFE®, APOLLO®, STELLA®, SIRIUS®, HYDROS®, HELIOS®, STRATOS®, MERKUR®), transfer line systems, cooling baths, cryostats, LHe valve boxes, control and monitoring technology as well as aluminium racking systems. The vessels are made predominantly of rust-free, cryogenic-tough stainless steel or aluminium and feature multi-layer vacuum superinsulation with highly active adsorbents. The manufacturing offer is complemented by cryo customizing & engineering as well as services ranging from planning through installation and commissioning to maintenance, including turnkey biobanks. Customers can be found in life science, medicine, pharma, research, laboratory, semiconductor, metal processing, food industry and aerospace. The company has been independent of gas suppliers since 2014 and is based in Kirchen (Sieg), Rhineland-Palatinate.

Site
Kirchen (Sieg)
Processes
Manufacture of vacuum-superinsulated cryogenic vessels (storage of deep-cold liquefied gases, incl., Cryo customizing & engineering (custom construction: cooling baths, LHe valve boxes, CryoCoolers,, Vacuum-superinsulated transfer line systems (rigid, flexible, multi-transfer lines,, Control and monitoring technology for cryogenics (CRYO LC®, LHe level gauge, BIOSAFE®, BIOSAFE® racks – racking systems for cryogenic storage (drawers, rack systems made of lightweight, Welding work on pressure vessels according to EN ISO 3834-2, manufacturing with quality controls, Services: planning, design, installation, commissioning, maintenance through to turnkey construction, Cooling baths with liquid nitrogen (cold shrink-fitting, cold milling, cooling application in the
Materials
Stainless steel (cryogenic-tough, highly corrosion-resistant), Aluminium (racks, ALPHA vessels, STRATOS® SL vessels), Adsorbent and getter materials (long-term vacuum protection), Stainless steel (cryogenic-tough), Aluminium, Adsorbent and getter materials, Welding according to EN ISO 3834-2
Certificates
DIN EN ISO 9001:2015, EN ISO 3834-2, EN ISO 13485:2016, Directive 93/42/EEC (Annex V), AD 2000 rulebook
Founded
1964 (Begi
Industries
Life Science, Medicine, Biobanks, Research, Laboratory, Pharma
  1. 01

    Engineering & design according to customer specifications

  2. 02

    Manufacture of vessels and assemblies (stainless steel/aluminium)

  3. 03

    Welding according to EN ISO 3834-2

  4. 04

    Quality control (X-ray inspection, helium leak testing)

  5. 05

    Assembly and functional testing at the plant

  6. 06

    Delivery, commissioning, maintenance

Materials & Processes

VA

Stainless steel (cryogenic-tough)

Cryogenic-tough and highly corrosion-resistant, used for cryogenic and sample storage vessels as well as transfer lines.

Al

Aluminium

Material for ALPHA and STRATOS® SL vessels as well as BIOSAFE® racks in lightweight design.

SI

Adsorbent and getter materials

Ensure long-term vacuum protection in vacuum-superinsulated vessels.

SCHW

Welding according to EN ISO 3834-2

Manufacture of pressure vessels with quality controls such as X-ray and helium leak testing.

Sites

Kirchen (Sieg)

DE

Headquarters and manufacturing plant

Materials
Stainless steel, aluminium

Industries

Life ScienceMedicineBiobanksResearchLaboratoryPharmaSemiconductorMetal processingFoodAerospaceEnvironmental researchBiobanks/BiorepositoriesIndustryLaser & welding technology

Processes & technical limits

ProcessesToleranceMax. partWeightLot sizeMaterials
Manufacture of vacuum-superinsulated cryogenic vessels (storage of deep-cold liquefied gases, incl.Other––––stainless steel, aluminium
Cryo customizing & engineering (custom construction: cooling baths, LHe valve boxes, CryoCoolers,Engineering––––stainless steel
Vacuum-superinsulated transfer line systems (rigid, flexible, multi-transfer lines,Other––––stainless steel
Control and monitoring technology for cryogenics (CRYO LC®, LHe level gauge, BIOSAFE®Engineering–––––
BIOSAFE® racks – racking systems for cryogenic storage (drawers, rack systems made of lightweightAssembly––––aluminium
Welding work on pressure vessels according to EN ISO 3834-2, manufacturing with quality controlsJoining––––stainless steel
Services: planning, design, installation, commissioning, maintenance through to turnkey constructionEngineering–––––
Cooling baths with liquid nitrogen (cold shrink-fitting, cold milling, cooling application in theOther–––––

Additional services

Cryo customizing & engineeringCustom construction/individual solutionsPlanningInstallation & commissioningMaintenanceTrainingTurnkey construction of biobanksSample management softwareRemote monitoring (CRYO-MESSENGER® / BIOSAFE® smart)

Quality & Certification

Custom systems are manufactured according to tested and approved drawings following a specific inspection sequence plan; before delivery, every system is assembled and functionally tested at the plant. Test methods include, among others, X-ray inspection and helium leak testing on welded pressure vessels.

EvidenceKirchen (Sieg)
DIN EN ISO 9001:2015
EN ISO 3834-2
EN ISO 13485:2016
Directive 93/42/EEC (Annex V)
AD 2000 rulebook

History

  1. 1964

    Start of vessel manufacturing, Gewerkschaft Siegtal

  2. 1979

    Founding of Siegtal Cryotherm GmbH

  3. 1980

    Acquisition by Messer Griesheim GmbH

  4. 2000

    Independent subsidiary of Messer Griesheim GmbH as Messer Cryotherm GmbH & Co. KG

  5. 2004

    Renamed Cryotherm GmbH & Co. KG and moved to the Air Liquide group

  6. 2014

    Takeover, continuation and further development of the core business by management – independent of gas suppliers

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