Development, production and distribution of medical toothpastes such as Ajona, Aminomed and Pearls & Dents since 1866
Dr. Rudolf Liebe Nachf. GmbH & Co. KG
Leinfelden-EchterdingenNew on Amplifa
About Dr. Liebe
Dr. Rudolf Liebe Nachf. GmbH & Co. KG is a family-owned company based in Leinfelden-Echterdingen that has specialized in the development, production and distribution of medical toothpastes since 1948. The product range includes the brands Ajona (since 1952 the first toothpaste concentrate on the market), Aminomed (medical fluoride-chamomile toothpaste) and Pearls & Dents with a patented, 100% biodegradable natural pearl system. The formulations rely on natural ingredients such as genuine chamomile flower extracts in organic quality, mint, geraniol and a dual-fluoride system; none of the products contains titanium dioxide. The toothpastes are manufactured at the site in Leinfelden-Echterdingen under the highest hygienic standards and in accordance with Cosmetic-GMP (ISO 22716), and are distributed in pharmacies, drugstores, food retail, dental practices and prophylaxis shops throughout Germany. Since mid-2025, the aluminium tubes have been made from 95% post-consumer recycled aluminium. Development takes place in close collaboration with dentists, orthodontists and universities.
- Site
- Leinfelden-Echterdingen
- Processes
- Manufacture of medical toothpastes (development, production and distribution), Manufacture of aluminium tubes from 95% post-consumer recycled aluminium, Development of medical toothpastes, Production, Distribution/marketing, Cooperation with dentists and universities, Provision of free samples for dentists, Periodontitis risk test
- Materials
- Aluminium (post-consumer recycled), Chamomile flower extract (organic quality), Dual-fluoride system, Natural pearl system
- Certificates
- ISO 22716 Cosmetic-GMP, ISO 9001, ISO 22716 (Cosmetic-GMP), Cruelty-free
- Founded
- 1866
- Industries
- Oral care, Dentistry, Pharmacies, Drugstores, Food retail, Dental practices
- 01
Development with dentists and universities
- 02
Formulation and production
- 03
Quality inspection according to Cosmetic-GMP
- 04
Distribution and marketing
Formulations and Materials
Chamomile flower extract (organic quality)
Natural, anti-inflammatory active ingredient in Aminomed.
Aluminium (post-consumer recycled)
Since mid-2025, the tubes consist of 95% post-consumer recycled aluminium.
Dual-fluoride system
Promotes remineralization and supports desensitization.
Natural pearl system
Patented pearl system made of 100% biodegradable care pearls in Pearls & Dents.
Locations
Leinfelden-Echterdingen
DEDevelopment, production and distribution
- Materials
- Chamomile flower extracts, mint, geraniol, fluoride, aluminium
Products
Inside the production
Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| Manufacture of medical toothpastes (development, production and distribution)Plastic | – | – | – | – | Chamomile flower extracts, Mint, Geraniol, Fluoride |
| Manufacture of aluminium tubes from 95% post-consumer recycled aluminiumForming | – | – | – | – | Aluminium (post-consumer recycled, 95%) |
Additional services
Quality and Certification
Production is carried out according to Cosmetic-GMP (DIN EN ISO 22716) with regular external audits; a quality management system according to DIN ISO 9001 for development, production and distribution is certified. Application studies from November 2021 and April 2025 confirm the products clinically-dermatologically and dentally with "very good".
| Evidence | Leinfelden-Echterdingen |
|---|---|
| ISO 9001 | |
| ISO 22716 (Cosmetic-GMP) | |
| Cruelty-free |
Company History
- 1866
Founded by pharmacist Johannes Paul Liebe in Dresden (dietetic and pharmaceutical preparations)
- 1895
First branch in Tetschen on the Elbe
- 1905
Tetschen branch becomes independent under pharmacist Willibald Liebe
- 1919
Dr. Rudolf Liebe takes over the company; runs it until the expropriation in 1948
- 1948
Refounding in Stuttgart-Möhringen; specialization in medical toothpastes
- 1952
Market launch of the toothpaste concentrate 'Ajona Stomaticum' – the first toothpaste concentrate on the market
- 1962
Relocation to Leinfelden-Echterdingen
- 1990
Market launch of Aminomed, developed with the University of Zurich
- 1995
Anniversary of the branch operation
- 1997
Market launch of Pearls & Dents, developed with Prof. Dr. F. G. Sander (University of Ulm), patented pearl system
- 2014
Pearls & Dents with nature-based pearl system (100% biodegradable care pearls); Aminomed receives a new design
- 2016
150 years of Dr. Liebe
- 2017
Ajona travel campaign with users worldwide
- 2018
Aminomed launches periodontitis risk test
- 2021
Aminomed newly formulated without titanium dioxide
- 2022
Pearls & Dents without titanium dioxide; 70 years of Ajona
- 2025
Since mid-2025, aluminium tubes made from 95% post-consumer recycled aluminium