Development and production of automated microfluidic workstations for ultrahigh-throughput screening of up to 10 million samples/24 h
Efficient Robotics GmbH
KornwestheimNew on Amplifa
About Efficient Robotics
Efficient Robotics GmbH was founded in 2012 and develops, produces and distributes automated microfluidic systems for the pharmaceutical, biotech and chemical industries. Its core product is the NTP (Nano-Titer-Pipe) Screening Workstation, a fully automated microfluidic workstation for ultrahigh-throughput screening of up to 10 million samples per 24 hours. The platform is used for screening and optimization of microbial strains, mammalian cell lines, enzymes, proteins and peptides. Droplets are actively generated with pressure and valve control and incubated as miniaturized reaction vessels under stable, identical conditions; assays can be added in 50–100 % of the sample volume. Detection is performed via highly sensitive fluorescence intensity (picomolar detection limit), fluorescence anisotropy, bioluminescence or light scattering, followed by automated hit selection and sorting. The Droplet Control Center software controls the processes and analyzes data in real time. The company is headquartered in Kornwestheim in the Stuttgart region and operates according to a DIN EN ISO 9001:2015 certified quality management system.
- Site
- Kornwestheim
- Processes
- Ultrahigh Throughput Screening (microfluidic droplet generation), Strain Optimization (microorganisms, mammalian cell lines), Enzyme and Antibody Optimization (Directed Evolution), Peptide Synthesis, Assay Addition (50–100 % of the sample volume) and Incubation, Cell incubation with controlled temperature and O2/CO2 supply, Development and production of laboratory equipment (DIN EN ISO 9001:2015, scope M18/M19), Development and production of automated microfluidic systems (NTP Screening Workstation)
- Materials
- Microorganisms, Mammalian cells, Enzymes, Proteins, Peptides, Mammalian Cells
- Certificates
- DIN EN ISO 9001:2015, ISO 9001
- Founded
- 2012
- Industries
- Pharmaceutical industry, Biotechnology, Chemical industry
- 01
- 02
Engineering of the microfluidic systems
- 03
Production of laboratory equipment
- 04
Integration of sensors, mechanics and software (Droplet Control Center)
- 05
Detection, selection and real-time data analysis
Systems and Applications
Microorganisms
Screening and strain optimization using ultrahigh-throughput methods.
Mammalian Cells
Incubation with controlled temperature and O2/CO2 supply.
Enzymes
Optimization via directed evolution in automated microfluidic process control.
Proteins
Screening and optimization on the NTP platform.
Peptides
Synthetic peptide generation at ultrahigh throughput.
Locations
Kornwestheim
DEHeadquarters, development and production
- NTP Screening Workstation (Nano-Titer-Pipe)
Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| Ultrahigh Throughput Screening (microfluidic droplet generation)Engineering | – | – | – | 10 million samples/24 h | – |
| Strain Optimization (microorganisms, mammalian cell lines)Engineering | – | – | – | – | – |
| Enzyme and Antibody Optimization (Directed Evolution)Engineering | – | – | – | – | – |
| Peptide SynthesisEngineering | – | – | – | – | – |
| Assay Addition (50–100 % of the sample volume) and IncubationEngineering | – | – | – | – | – |
| Inspection | – | – | – | – | – |
| Cell incubation with controlled temperature and O2/CO2 supplyEngineering | – | – | – | – | – |
| Development and production of laboratory equipment (DIN EN ISO 9001:2015, scope M18/M19)Engineering | – | – | – | – | – |
1 Anlagen & Maschinen
| Machine | Manufacturer / model | Quantity | Working area | Year built | Site |
|---|---|---|---|---|---|
| Microfluidic Screening Workstation (Nano-Titer-Pipe) | Efficient Robotics NTP Screening Workstation | – | – | – | Kornwestheim |
Additional services
Quality
The quality standards are implemented in a quality management system certified to DIN EN ISO 9001:2015 for the development and production of laboratory equipment (FOX Certification GmbH, certificate ZN-2017-16).
| Evidence | Kornwestheim |
|---|---|
| ISO 9001 |
History
- 2012
Foundation of Efficient Robotics
- 2017
Certification of the quality management system according to DIN EN ISO 9001:2015 (certificate dated 22.11.2017, valid until 21.11.2020)