Manufacturer of herbal cough medicines based on the ivy special extract EA 575, Made in Germany.

Engelhard Arzneimittel GmbH & Co. KG

Niederdorfelden (Headquarters, Production)New on Amplifa

1950Market launch of Prospan cough drops

5Generations of family business

Over 100 countriesExport countries

NiederdorfeldenSite (Hesse)

About Engelhard Arzneimittel

Engelhard Arzneimittel is a family business from Niederdorfelden in Hesse, now run in its fifth generation, specialising in the development and manufacture of herbal medicines (phytopharmaceuticals). The company is the manufacturer of the Prospan product family for the treatment of cough and bronchitis, which is based on the specially developed ivy special extract EA 575 made from ivy leaves (Hedera helix). At its own site in Niederdorfelden, the active ingredient is extracted and various dosage forms are produced, including cough syrup, cough liquid in bottles and stick packs, pastilles and effervescent tablets. A dedicated research department conducts basic research and clinical studies; in 2003, the company's scientists decoded the mode of action of the active ingredient alpha-Hederin. The products are exported to over 100 countries and documented in five languages (German, English, Turkish, Arabic, Russian). All Prospan medicines are manufactured in Germany.

Site: Niederdorfelden
Processes: Manufacture of herbal medicines (phytopharmaceuticals), Extraction of ivy special extract EA 575, Research and development (clinical studies), Export to over 100 countries
Materials: Ivy special extract EA 575 (ivy leaf dry extract), alpha-Hederin
Industries: Pharmaceuticals, OTC medicines, Phytotherapy

01
Cultivation and raw material sourcing (ivy from Germany/Europe)
02
Extraction of ivy special extract EA 575
03
Manufacture of the medicines
04
Quality assurance
05
Distribution and export to over 100 countries

Active Ingredients and Processes

EA 575

Ivy special extract EA 575 (ivy leaf dry extract)

Herbal active ingredient from Hedera helix, obtained through an exclusive, specially developed extraction process; mucolytic, antispasmodic, expectorant and soothing.

α-Hed

alpha-Hederin

Active ingredient whose mode of action was decoded by the company's scientists in 2003.

Sites

Niederdorfelden

Headquarters, production and extraction

Materials: Ivy special extract EA 575

Products

**Prospan cough syrup for children**Liquid for oral administration · Paediatrics/OTC

**Prospan cough liquid in the bottle**Liquid for oral administration · OTC

**Prospan cough liquid in stick packs**Stick pack · OTC

**Prospan cough effervescent tablets**Effervescent tablets · OTC

**Prospan cough pastilles**Pastilles · OTC

**Prospan cough drops**Liquid for oral administration · OTC

Inside the production

Prospan cough liquid, stick pack package

Industries

PharmaceuticalsOTC medicinesPhytotherapy

Additional services

Manufacture of herbal medicines (phytopharmaceuticals)Extraction of ivy special extract EA 575Research and development (clinical studies)Export to over 100 countries

History

1940er
Dr. Karl Engelhard researches a remedy for his daughter Gloria suffering from whooping cough and discovers the effect of ivy on respiratory infections
1950
Market launch of Prospan cough drops
1991
Market launch of Prospan cough syrup (sugar-free, child-friendly cherry flavour)
2003
Engelhard scientists decode the mode of action of the active ingredient alpha-Hederin
2005
Market launch of Prospan cough liquid sticks
2019
Prospan is recommended in the guideline for the treatment of acute cough in adults
2025
75 years of Prospan – Made in Germany