Automated laboratory and pilot-scale systems, reactor systems and process automation for chemical and biotechnological process development.
HITEC ZANG GmbH
Herzogenrath (Kohlscheid)New on Amplifa
About HITEC ZANG
HITEC ZANG GmbH, based in Herzogenrath, has been developing and manufacturing hardware and software for chemical and biotechnological process development for over 40 years, including pressure reactor systems for nearly 20 years. The portfolio comprises automated laboratory and pilot-scale systems for batch and continuous processes, laboratory reactor systems made of borosilicate glass and stainless steel, turnkey pressure reactor systems from 10 mL to 100 L (up to 200 bar), microreaction systems, custom bioreactors as well as cell culture and fermenter systems including the RAMOS measurement system for online respiration activity monitoring. This is complemented by process automation with LabVision software, LabManager and LabBox, dosing technology, safety switchgear cabinets as well as retrofit and modernization of existing systems. Materials include borosilicate glass, stainless steel 1.4404/1.4571, 1.4876, PTFE and Hastelloy; material certificates according to FDA, GMP and ATEX options are available. The interdisciplinary team of around 60 specialists serves industries such as chemicals, pharmaceuticals, biotechnology, cosmetics, food and environmental technology as well as battery recycling and hydrogen production. Components of the pressure reactor systems are manufactured in cooperation with suppliers such as JUCHHEIM Laborgeräte GmbH, Wilhelm-Schmidt, DeDiedrich, Swagelok and Wika; production takes place in Germany.
- Site
- Herzogenrath
- Processes
- Custom plant engineering (tailor-made laboratory systems), Batch systems (reactor systems), Continuous systems (continuous reactor systems), Microreaction systems / microreaction technology, Tube reactors, Pilot-scale systems, Prototype systems (e.g. battery recycling, green hydrogen, NH3 decomposition in a fixed-bed reactor), Retrofit of existing systems (chemicals, biotechnology)
- Materials
- Borosilicate glass, Stainless steel 316L, Stainless steel 1.4404/1.4571, PTFE, Stainless steel 1.4571, Stainless steel 1.4876, Hastelloy
- Certificates
- ISO 9001:2015, ISO 9001
- Industries
- Chemicals, Pharmaceuticals, Biotechnology, Cosmetics, Food technology, Environmental technology
- 01
Requirements analysis and consulting
- 02
Concept development and engineering
- 03
Design and software development
- 04
Manufacturing and integration of the system
- 05
Acceptance testing (FAT) in Herzogenrath
- 06
On-site commissioning and user training
- 07
Support, process optimization and retrofit
Materials & Processes
Borosilicate glass
For laboratory reactors and bioreactors in batch operation at temperatures from −80 °C to +300 °C.
Stainless steel 316L
For batch systems and bioreactor systems, available FDA- and GMP-compliant.
Stainless steel 1.4571
For continuous systems and pressure reactor systems up to 200 bar.
Stainless steel 1.4876
For continuous reactor systems at elevated operating temperatures.
PTFE
For corrosion-resistant components in laboratory systems and bioreactors.
Hastelloy
For pressure reactor systems with aggressive media and high-pressure applications.
Locations
Herzogenrath (Kohlscheid)
DEHeadquarters, development, manufacturing, sales
- Part weight / size
- Reactor volume 10 mL – 100 L
- Lot size
- Individual systems and custom systems
- Materials
- Borosilicate glass, stainless steel 1.4404/1.4571, 1.4876, PTFE, Hastelloy
- LabManager automation system
- LabBox laboratory automation
- RAMOS measurement system (8-fold parallel)
- SyrDos syringe pump
- Gmix precision gas mixing station
- 80 L pilot-scale system (incl. SAT)
Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| Custom plant engineering (tailor-made laboratory systems)Engineering | – | – | – | – | – |
| Batch systems (reactor systems)Engineering | – | – | 10 mL – 100 L | – | Borosilicate glass, Stainless steel 316L, PTFE |
| Continuous systems (continuous reactor systems)Engineering | – | – | 10 mL – 3 L | – | 1.4571, 1.4876 |
| Microreaction systems / microreaction technologyEngineering | – | – | – | – | – |
| Tube reactorsEngineering | – | – | – | – | – |
| Pilot-scale systemsEngineering | – | – | – | – | – |
| Prototype systems (e.g. battery recycling, green hydrogen, NH3 decomposition in a fixed-bed reactor)Engineering | – | – | – | – | – |
| Retrofit of existing systems (chemicals, biotechnology)Engineering | – | – | – | – | – |
| Pressure reactor systems (high-pressure systems, turnkey 0.1–100 L)Engineering | – | – | 10 mL – 100 L | – | Borosilicate glass, Stainless steel 1.4404/1.4571, Hastelloy |
| Pressure reactor applications: polymerizations, hydrogenations, syngas reactionsEngineering | – | – | – | – | Stainless steel (1.4404/1.4571), Hastelloy, Glass |
| Custom bioreactors and systems (shaken and stirred)Engineering | – | – | 10 mL – 100 L | – | Borosilicate glass, Stainless steel 316L, PTFE |
| Cell culture & fermenter systems (bacteria, yeasts, fungi, plant/animal cell cultures)Engineering | – | – | – | – | – |
| Retrofit of bioreactor systems / prototype systems in the bio sectorEngineering | – | – | – | – | – |
| Process automation for laboratory, pilot scale and miniplant (software LabVision, LabManager,Engineering | – | – | – | – | – |
| Dosing technology (pumps & dosing devices)Engineering | – | – | – | – | – |
| Safety switchgear cabinetsEngineering | – | – | – | – | – |
| RAMOS bioprocess optimization in shake flasks (online respiration activity measurementTesting | – | – | – | – | – |
| Emulsion polymerization, dispersion and reactor weighing (fed-batch and recirculation operation)Engineering | – | – | – | – | Stainless steel |
8 Anlagen & Maschinen
| Machine | Manufacturer / model | Quantity | Working area | Year built | Site |
|---|---|---|---|---|---|
| LabBox automation system (compact laboratory automation) | HITEC ZANG LabBox | – | Dimensions (WxHxD): 222 x 58 x 124 mm | – | – |
| LabManager automation device | HITEC ZANG LabManager | – | – | – | – |
| RAMOS measurement system (Respiration Activity MOnitoring System, 8-fold parallel) | HITEC ZANG RAMOS | – | – | – | – |
| Syringe pump | HITEC ZANG SyrDos | – | – | – | – |
| Component manufacturing in cooperation with JUCHHEIM Laborgeräte GmbH | JUCHHEIM Laborgeräte GmbH | – | – | – | – |
| Component cooperation partner (pressure reactors) | Wilhelm-Schmidt GmbH; DeDiedrich; Swagelok; Wika | – | – | – | – |
| Gas mixing station | HITEC ZANG Gmix precision gas mixing station | – | – | – | – |
| Pilot-scale system | HITEC ZANG 80 L pilot-scale system (flexible, incl. SAT) | – | – | – | – |
Additional services
Reference customers
Quality
HITEC ZANG is certified according to ISO 9001:2015 (TÜV NORD CERT, initial certification 2022); the scope covers the development, manufacture and sale of software, devices and systems for chemical and biotechnological process development including user training. Pressure reactor systems are designed according to DGRL and MachRL and inspected by a notified body.
| Evidence | Herzogenrath (Kohlscheid) |
|---|---|
| ISO 9001 |
History
- 1980
Founded by Prof. Dr.-Ing. Werner Zang as an engineering office for custom hardware and software development.
- 1980er
Development of the first process control system for process engineering and of the LabManager-Classic as an automation component.
- 1993
Introduction of the LabVision software for monitoring, control and regulation of automated reactors.
- seit 1997
Planning and implementation of turnkey laboratory and pilot systems.
- 2013
Expansion of production areas by approx. 900 m².
- 2016
Acquisition of the apparatus supplier Juchheim Laborgeräte GmbH.
- 2020
Presentation of the LabBox as a compact system for entering the digital laboratory.
- 2023
Opening of the demo laboratory for customer visits, training and internal research.
- 2022
Initial certification according to ISO 9001:2015 (TÜV NORD CERT).