Development and distribution of native cytoskeleton proteins, ATTO conjugates and assay reagents for quantitative cell biology
HYPERMOL EK
Bielefeld (Theesener Str. 7A) · Bielefeld (P.O. Box 201025)New on Amplifa
About Hypermol
Hypermol is a Bielefeld-based, owner-managed company (e.K.) that develops and distributes reagents for cytoskeleton research. The portfolio includes native, tissue-isolated proteins such as actin from rabbit skeletal muscle and non-muscle actin (beta/gamma) from porcine brain, recombinant actin-binding proteins such as profilin and CapZ, as well as native gelsolin. In addition, spectrally defined ATTO fluorophore conjugates for TIRF/TIRFM microscopy, fluorophore-conjugated secondary antibodies, buffers, staining kits and stabilized, pre-buffered nucleotide formulations (ATP, GTP, ATPγS, GTPγS, AMP-PNP) are offered. The proteins are produced using native purification processes and bioconjugation; quality is documented by SDS-PAGE and densitometry, with product datasheets and handling guides for each product. Services include custom synthesis, technical support and preparation of MSDSs and datasheets. The company supplies life science research laboratories worldwide via express shipping, with a commitment to dispatch within 24 hours for stock items.
- Site
- Bielefeld
- Processes
- Protein Purification (native, tissue-isolated), Fluorophore/Bioconjugation (ATTO- and other fluorophore-conjugated reagents), Custom Synthesis, Product quality & analysis (QC, product datasheets), Custom Synthesis (technical inquiries), Technical support on product handling, quality & analysis, MSDSs and product datasheets, Free actin sample (250 µg alpha-actin)
- Materials
- Actin (rabbit skeletal muscle alpha-actin), Non-muscle Actin (beta/gamma, porcine brain), Profilin (human recombinant), CapZ (human recombinant), Gelsolin (native, porcine smooth muscle), ATP / GTP / ADP / AMP / ATPγS / GTPγS / AMP-PNP (Nucleotide formulations), Non-Muscle Actin (beta/gamma, porcine brain), ATP/GTP/Nucleotide Analogs (stabilized formulations)
- Certificates
- Satisfaction Guarantee
- Industries
- Cytoskeleton research, Biochemistry, Life science research, High-resolution fluorescence microscopy (TIRF/TIRFM)
- 01
Native protein purification (tissue isolation)
- 02
Recombinant protein expression/purification
- 03
Fluorophore bioconjugation (ATTO and others)
- 04
Quality control & analysis (SDS-PAGE, densitometry)
- 05
Packaging & documentation
- 06
Worldwide express shipping
Proteins & Reagents
Actin (rabbit skeletal muscle alpha-actin)
Native, polymerization-competent skeletal muscle actin for polymerization and TIRF assays.
Non-Muscle Actin (beta/gamma, porcine brain)
Native non-muscle actin, immediately soluble and fully polymerization-competent (~99 % pure).
Profilin (human recombinant)
Human recombinant, unlabeled actin-sequestering protein inhibitor with >95 % purity.
CapZ (human recombinant)
Recombinant heterodimer (>96 % pure) for capping F-actin barbed ends and for G-actin nucleation.
Gelsolin (native, porcine smooth muscle)
Native, tissue-isolated actin-binding protein.
ATP/GTP/Nucleotide Analogs (stabilized formulations)
Pre-buffered dry formulations (pH 7.4), assay-ready immediately after reconstitution.
Locations
Bielefeld
DECompany headquarters, development and distribution
Products
Inside the production
Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| Protein Purification (native, tissue-isolated)Engineering | – | – | – | – | – |
| Fluorophore/Bioconjugation (ATTO- and other fluorophore-conjugated reagents)Engineering | – | – | – | – | – |
| Custom SynthesisEngineering | – | – | – | – | – |
| Product quality & analysis (QC, product datasheets)Testing | – | – | – | – | – |
Additional services
Quality
Product quality is documented by SDS-PAGE and scanning densitometry (purities of e.g. ~99 % or >95–99 % depending on the product); each product comes with datasheets and handling guides. A Satisfaction Guarantee applies to the products.
| Evidence | Bielefeld |
|---|---|
| Satisfaction Guarantee |