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HyPhoX – Fertigung

HyPhoX develops photonic biosensor chips and portable analysis devices for digital rapid tests with laboratory quality.

HyPhoX Logo

HyPhoX GmbH

WildauNew on Amplifa

2021Leibniz Founders' Prize
< 10 minAnalysis time
2 mm²Chip size
≤ 8Analytes in parallel on one chip
200 mmWafer diameter

About HyPhoX

HyPhoX is a deep-tech company from the Berlin-Brandenburg region, headquartered in Wildau. The company develops photonic biosensor chips on which photonics, microelectronics and biochemistry are combined on an area of 2 mm². The sensors are based on photonic integrated circuits fabricated in an industrially scalable CMOS technology on 200-mm silicon wafers; the patented manufacturing process takes place directly on the wafer and is scalable to series production. Up to eight analytes are detected quantitatively and in parallel on a single chip in real time. The product portfolio includes, in addition to the biosensor chips, an 8-channel readout and control board with low-noise photocurrent measurement as well as laser and TEC drivers, and a portable prototype system for on-site measurements. The AI-powered analysis delivers results in less than ten minutes. Application fields are point-of-care diagnostics, water analysis, food diagnostics and environmental monitoring.

Site
Wildau
Processes
CMOS technology (photonic integrated circuits), Wafer-level production of photonic biosensors, Photonic biosensor analytics (digital rapid tests, multiplex up to 8 analytes), 8-channel readout electronics (low-noise photocurrent measurement, laser and TEC drivers), AI-powered analysis, Prototype systems for on-site measurements, 8-channel readout electronics (Readout & Control Board), Photonic biosensor chips (wafer-level production)
Materials
Silicon, Photonic integrated circuits, CMOS technology, AI-powered analysis
Certificates
EXIST funding (BMWK)
Industries
Point-of-care diagnostics, Water analysis, Food diagnostics, Environmental monitoring
  1. 01

    Wafer-level production of photonic biosensors (CMOS technology)

  2. 02

    8-channel readout electronics (Readout & Control Board)

  3. 03

    Integration into prototype system (portable analysis device)

  4. 04

    AI-powered data analysis and result output

Materials & Technologies

Si

Silicon

Substrate material for photonic integrated circuits and biosensor chips in CMOS technology.

PIC

Photonic integrated circuits

Optical, electronic and microfluidic components combined on a single chip.

CMOS

CMOS technology

Industrially scalable manufacturing process for the wafer-level production of the biosensors.

ML

AI-powered analysis

Machine-learning algorithms for quantitative results and real-time trend analyses.

Locations

Standort Wildau

Wildau

DE

Development and Manufacturing

Part weight / size
Chip size 2 mm² · Wafer 200 mm
Lot size
Prototype to series production (wafer-level production)
Materials
Silicon
  • Prototype system (portable analysis device)
  • Readout & Control Board (8-channel readout electronics)

Products & Components

Biosensor chip (2 mm²)
Biosensor chip (2 mm²)Wafer-level production · Point-of-care diagnostics
Silicon wafer with photonic biosensors
Silicon wafer with photonic biosensorsCMOS technology · Series production
Readout & Control Board
Readout & Control Board8-channel readout electronics · Analytics
Prototype system
Prototype systemPortable analysis device · On-site measurements

Inside the production

Biosensor chip with smartphone evaluation
Biosensor chip with smartphone evaluation
Innovation Award Berlin Brandenburg 2023
Innovation Award Berlin Brandenburg 2023

Industries

Point-of-care diagnosticsWater analysisFood diagnosticsEnvironmental monitoring

Processes & technical limits

ProcessesToleranceMax. partWeightLot sizeMaterials
CMOS technology (photonic integrated circuits)Testing–200 mm (wafer)–Series production (wafer-levelSilicon
Wafer-level production of photonic biosensorsSurface––––Silicon
Photonic biosensor analytics (digital rapid tests, multiplex up to 8 analytes)Testing–2 mm² chip size–––
8-channel readout electronics (low-noise photocurrent measurement, laser and TEC drivers)Assembly–––––

2 Anlagen & Maschinen

MachineManufacturer / modelQuantityWorking areaYear builtSite
Prototype system (portable analysis device)HyPhoX–––Wildau
Readout & Control Board (8-channel readout electronics)HyPhoX–––Wildau

Additional services

AI-powered analysisPrototype systems for on-site measurements8-channel readout electronics (Readout & Control Board)Photonic biosensor chips (wafer-level production)

Quality

The sensor technology enables quantitative digital rapid tests with laboratory quality and analysis times of less than ten minutes; up to eight analytes are detected in parallel on a single chip.

EvidenceWildau
EXIST funding (BMWK)

History & Awards

  1. 2021

    Leibniz Founders' Prize of the Leibniz Association

  2. 2023

    Main prize, Innovation Award Berlin Brandenburg; main prize, Startup Competition Digital Innovations (BMWK, endowed with €32,000); EXIST funding (BMWK) since 2023

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