
Develops MRI/ultrasound fusion systems and 3D mapping software for prostate biopsy
KOELIS SAS
Grenoble (FR) · Princeton, NJ (US) · Hong Kong (HK) · Homberg (DE)New on Amplifa
About KOELIS
KOELIS is a medical technology manufacturer specializing in prostate cancer diagnostics and therapy, headquartered in Grenoble, France. The company develops and markets the KOELIS Trinity® fused MRI/ultrasound biopsy system as well as the patented OBT Fusion® technology (Organ Based Tracking Fusion), which automatically captures prostate movement and documents each biopsy site three-dimensionally with millimetric accuracy. Further products include a 3D ultrasound platform with automatic motion compensation, the 2nd-look option for active surveillance, and ProMap® Smart. The solutions are used by urologists and radiologists from diagnosis to treatment, and since 2017 also for the transperineal biopsy approach. According to the company, KOELIS technology is represented in over 500 clinical publications and has been used on more than 1,000,000 patients worldwide. In addition to its headquarters in Grenoble, KOELIS maintains branches in Princeton (USA), Hong Kong, and Homberg (Germany).
- Site
- Grenoble
- Processes
- MRI/US Fusion Prostate Biopsy (3D prostate mapping), OBT Fusion® (Organ Based Tracking Fusion), 3D Ultrasound imaging with automatic movement compensation, 2nd look fusion biopsy option, Transperineal biopsy approach, Image Guided Surgery in Urology, 3D prostate mapping / MRI-US fusion biopsy software (OBT Fusion®), KOELIS Trinity® MRI/US fusion biopsy system
- Materials
- OBT Fusion® (Organ Based Tracking Fusion), 3D Ultrasound, MRI/US Fusion (KOELIS Trinity®), 2nd look option, Transperineal access (since 2017)
- Founded
- 2006
- Industries
- Medical technology, Urology, Radiology, Oncological diagnostics (prostate cancer), Medical technology / Medical technology, Prostate cancer diagnostics and therapy
- 01
Research & clinical development
- 02
Software development (3D mapping, fusion imaging)
- 03
System development & integration (Trinity®)
- 04
Sales & consulting
- 05
Clinical use & training
Technologies & Processes
OBT Fusion® (Organ Based Tracking Fusion)
Patented technology that automatically captures prostate movements and deformations and documents each biopsy site with millimetric accuracy.
3D Ultrasound
Ultrasound platform that is the only one to automatically compensate for prostate and patient movements; only the ultrasound probe is required as hardware.
MRI/US Fusion (KOELIS Trinity®)
Fully integrated mobile fusion imaging platform for personalized prostate care from diagnosis to therapy.
2nd look option
Safeguarding clinical decisions through biopsy of sampled and non-sampled areas, among other things for active surveillance.
Transperineal access (since 2017)
Transperineal biopsy approach for patient-friendly, precise tissue sampling.
Locations

Grenoble
FRGlobal headquarters (development & sales)
- Materials
- MRI/US Fusion, 3D Ultrasound, OBT Fusion®
- KOELIS Trinity® MRI/US fusion system
- 3D ultrasound platform
Princeton, NJ
USUSA subsidiary (since 2015)
- Materials
- MRI/US Fusion, 3D Ultrasound
- KOELIS Trinity® MRI/US fusion system
Hong Kong
HKAsia office (since 2019)
- Materials
- MRI/US Fusion
Homberg
DEGerman subsidiary (since 2022)
- Materials
- MRI/US Fusion, 3D Ultrasound
- KOELIS Trinity® MRI/US fusion system
Systems & Products



Inside the production




Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| MRI/US Fusion Prostate Biopsy (3D prostate mapping)Testing | millimetric accuracy | – | – | – | – |
| OBT Fusion® (Organ Based Tracking Fusion)Testing | millimetric accuracy | – | – | – | – |
| 3D Ultrasound imaging with automatic movement compensationTesting | – | – | – | – | – |
| 2nd look fusion biopsy optionTesting | – | – | – | – | – |
| Transperineal biopsy approachTesting | – | – | – | – | – |
| Image Guided Surgery in UrologyTesting | – | – | – | – | – |
2 Anlagen & Maschinen
| Machine | Manufacturer / model | Quantity | Working area | Year built | Site |
|---|---|---|---|---|---|
| MRI/US Prostate Biopsy System (fully integrated mobile fusion imaging platform) | KOELIS Trinity® | – | – | – | Grenoble (HQ); Princeton NJ; Hong Kong; Homberg (Germany) |
| Ultrasound prostate probe (only hardware required) | KOELIS | – | – | – | – |
Additional services
History
- 2001
Antoine Leroy and Patrick Henri develop image-guided surgery in urology
- 2006
Foundation of KOELIS® in Grenoble
- 2009
Market launch of mapping and fusion imaging software
- 2011
First financing round with Medevice Capital
- 2015
Establishment of the US subsidiary in Princeton, NJ
- 2017
Introduction of the transperineal biopsy approach
- 2019
Opening of the Asia office in Hong Kong; equity round with InnovaHealth Partners
- 2022
Establishment of the German subsidiary; Series B growth round with InnovaHealth Partners