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Lumiprobe – Fertigung

Manufacturer of fluorescent dyes and bioconjugation reagents for life science and oligonucleotide synthesis

Lumiprobe Logo

Lumiprobe Corporation

Westminster, MD (USA)New on Amplifa

20+ yearsOn the market (according to website)
4,000+Products
100+Countries served
7,000+Citations in publications

About Lumiprobe

Lumiprobe Corporation is a US-based manufacturer of fluorescent dyes, quenchers and bioconjugation reagents headquartered in Westminster, Maryland. The portfolio comprises more than 4,000 products: cyanine, fluorescein, rhodamine and BDP dyes with reactive groups (NHS esters, azides, alkynes, maleimides, hydrazides, tetrazines, DBCO, TCO), oligonucleotide synthesis reagents such as phosphoramidites and CPG, protein, nucleic acid and cell biology reagents as well as conjugates with BSA and streptavidin. A focus is a click chemistry-based technology for oligonucleotide labeling with high yield and purity. Every batch is analytically tested (NMR, HPLC-MS, UV-VIS) and documented with an electronic Certificate of Analysis; the raw data are available for download. The products are shipped to more than 100 countries and, according to the company, are cited in over 7,000 scientific publications.

Site
Westminster, MD, USA
Processes
Manufacture of fluorescent dyes and bioconjugation reagents (life science reagents), Analytical quality assurance (NMR, HPLC-MS, UV-VIS), Electronic Certificates of Analysis (CoA), Retest program for product batches, Technical support, Click chemistry-based oligonucleotide labeling technology
Materials
BSA (bovine serum albumin) conjugates, Streptavidin conjugates, Cyanine dyes, Fluorescein (FAM) derivatives, BODIPY/BDP dyes, Phosphoramidites and CPG, Protein conjugates (BSA, streptavidin), Mass spectrometry reagents
Certificates
ISO 9001:2015
Industries
Biotechnology, Life Science Research, Pharmaceutical Industry, Molecular Imaging, Diagnostics, Oligonucleotide Synthesis
  1. 01

    Synthesis of fluorescent dyes and reagents

  2. 02

    Analytical testing (NMR, HPLC-MS, UV-VIS)

  3. 03

    Electronic quality system and CoA generation

  4. 04

    Sales and worldwide shipping

  5. 05

    Technical support and retest program

Product Groups and Processes

Cy

Cyanine dyes

Water-soluble and sulfonated derivatives for protein and oligonucleotide labeling from UV to NIR.

FAM

Fluorescein (FAM) derivatives

Reactive maleimide, NHS ester and tetrazine forms for thiol and amine labeling.

BDP

BODIPY/BDP dyes

Hydrophobic borondipyrromethene dyes, e.g. for lipid staining.

PhA

Phosphoramidites and CPG

Alkyne- and BCN-modified amidites for oligonucleotide synthesis and click labeling.

Conj

Protein conjugates (BSA, streptavidin)

Ready-to-use fluorescent conjugates for immunofluorescence and assays.

LPC

Mass spectrometry reagents

Lysophosphatidylcholines as internal standards for LC-MS studies.

Chel

DOTA chelators

Thiol-reactive bifunctional chelators for radiopharmaceuticals and molecular imaging.

Locations

Westminster, MD

US

Headquarters, laboratory and customer service

Materials
Fluorescent dyes, bioconjugation reagents
  • NMR spectrometer
  • HPLC-MS system
  • UV-VIS spectrophotometer

Products

ROX Tetrazine, 5-Isomer
ROX Tetrazine, 5-IsomerCopper-free Click Chemistry · Bioconjugation
sulfo-Cyanine3 DBCO
sulfo-Cyanine3 DBCOCopper-free Click Chemistry · Bioconjugation
Alkyne dT Phosphoramidite
Alkyne dT PhosphoramiditeOligonucleotide Synthesis · Life Science
BDP 650/665 Lipid stain
BDP 650/665 Lipid stainStaining Reagent · Cell Biology
FAM Maleimide, 6-Isomer
FAM Maleimide, 6-IsomerThiol Labeling · Protein Labeling
C26:0-Lysophosphatidylcholine
C26:0-LysophosphatidylcholineLC-MS Standard · Mass Spectrometry
Maleimido-mono-amide-DOTA
Maleimido-mono-amide-DOTABifunctional Chelator · Molecular Imaging
CytoTracer® Blue CMAC
CytoTracer® Blue CMACCell Staining Reagent · Cell Biology

Inside the production

Fluorescent BSA conjugates
Fluorescent BSA conjugates
New TCO reagents for bioorthogonal conjugation
New TCO reagents for bioorthogonal conjugation
CytoTracer® dyes for cell tracing
CytoTracer® dyes for cell tracing

Industries

BiotechnologyLife Science ResearchPharmaceutical IndustryMolecular ImagingDiagnosticsOligonucleotide Synthesis

Processes & technical limits

ProcessesToleranceMax. partWeightLot sizeMaterials
Manufacture of fluorescent dyes and bioconjugation reagents (life science reagents)Engineering––––Chemical reagents, Fluorescent dyes, Oligonucleotides

3 Anlagen & Maschinen

MachineManufacturer / modelQuantityWorking areaYear builtSite
NMR spectrometer––––Lumiprobe
HPLC-MS system––––Lumiprobe
UV-VIS spectrophotometer––––Lumiprobe

Additional services

Analytical quality assurance (NMR, HPLC-MS, UV-VIS)Electronic Certificates of Analysis (CoA)Retest program for product batchesTechnical supportClick chemistry-based oligonucleotide labeling technology

Quality

Every batch is tested by NMR, HPLC-MS and UV-VIS and documented with an electronic Certificate of Analysis whose raw data customers can access. An electronic quality system (since 2013), batch numbers and regular retests ensure traceability; the QM system is certified to ISO 9001:2015.

EvidenceWestminster, MD
ISO 9001:2015

History

  1. Website advertises '20+ Years in business' (no explicit founding year given)

  2. 2012

    Introduction of a batch numbering system for batch identification

  3. 2013

    Introduction of an electronic quality system

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