Compact benchtop microdispensing systems for picoliter to microliter precise liquid dosing
M2-Instruments GmbH
Wildau, Brandenburg, GermanyNew on Amplifa
About M2-Instruments
M2-Instruments GmbH develops and manufactures compact benchtop microdispensing systems for the reliable handling of sensitive liquids. The flagship iFOUR enables contact-free dosing from 10 picoliters to 1 microliter and is designed for microarray printing, biosensor functionalization, and loading of lab-on-a-chip and microfluidics chips. The technology portfolio includes the Piezo-Driven Microdispenser (PDMD/PDMD-L) with up to 1000 drops per second, the Aspirate/Dispense dispenser M2MD AD (10 nL to 5 µL), and the Bulk Dispenser M2MD BD. The systems process proteins, aptamers, oligonucleotides, antibodies, DNA, and enzymes on substrates such as slides, membranes, chips, and microtiter plates. The company was founded in 2019 and is based in Wildau near Berlin; the sister company and parent organization is M2-Automation GmbH, which delivers custom multi-channel systems for scalable production. Sales, service, and support are provided worldwide, including via authorized distributors in the Americas, China, as well as Australia and New Zealand.
- Site
- Wildau
- Processes
- Microdispensing (contact-free, pL–µL), Piezo-Driven Microdispensing (PDMD/PDMD-L), Aspirate/Dispense Microdispensing (M2MD AD, Flow-Based), Bulk Dispensing (M2MD BD), Microarray Printing, Biosensor functionalization (coating), Lab-on-a-Chip / microfluidics loading, Assay miniaturization
- Materials
- Borosilicate glass, Borosilicate glass capillary, Piezo ceramic actuator, Glass vial, Proteins, Aptamers, Oligonucleotides, Antibodies
- Certificates
- Spot detection / quality control (head camera), ISO 9001
- Founded
- 2019
- Industries
- Diagnostics, Biotechnology, Life Sciences, Pharmaceutical research, Biosensorics, Lab-on-a-Chip/Microfluidics
- 01
Engineering and design
- 02
Custom build of the iFOUR systems to customer specification
- 03
Online configurator and quote request
- 04
Integration of dispensers (PDMD, M2MD AD, M2MD BD)
- 05
Quality control via spot detection with integrated head camera
- 06
Sales, service and support worldwide (EX-Works, distributors)
Dispensed substances and dispenser technologies
Piezo-Driven Microdispenser
Contact-free picoliter dosing from 20–30 pL at up to 1000 drops/s with pulse shaper for application-specific pulse adjustment.
PDMD Type L
High-capacity piezo dispenser for an extended volume range with fewer changes in the workflow.
M2 Microdispenser Aspirate/Dispense
Aspirates and dispenses liquids from 10 nL to 5 µL with three interchangeable glass tips.
M2 Microdispenser Bulk Reservoir
Bulk dispensing of a solution from a 20-mL glass vial from the nanoliter down to the lower microliter range.
Borosilicate glass
Capillary material of the piezo dispensers for precise droplet formation.
Piezoceramic actuator
Actuates the volume displacement in the PDMD for ultra-fast dosing.
Locations
Wildau
DEHeadquarters: development, custom build, sales, service and support
- Lot size
- Single units to small series (custom build)
- Materials
- Borosilicate glass, piezoceramic
- iFOUR benchtop microdispensing instrument
- PDMD/PDMD-L piezo dispenser
- M2MD AD aspirate/dispense dispenser
- M2MD BD bulk dispenser
- iFOUR wash station with droplet camera
- Dummy PDMD (teaching accessory)
Systems and dispensers
Inside the production
Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| Microdispensing (contact-free, pL–µL)Joining | – | – | 10 pL – 1 µL | – | Proteins, Aptamers, Oligonucleotides, Antibodies, DNA, Enzymes, Reagents |
| Piezo-Driven Microdispensing (PDMD/PDMD-L)Joining | – | – | 20–30 pL | up to 1000 drops/s | sensitive liquids/samples |
| Aspirate/Dispense Microdispensing (M2MD AD, Flow-Based)Joining | – | – | 10 nL – 5 µL | – | liquids |
| Bulk Dispensing (M2MD BD)Joining | – | – | nanoliter – low microlitre | – | liquids (single solution), 20 mL glass vial |
| Microarray PrintingJoining | – | – | – | – | Proteins, DNA, Antibodies, Slides, Membranes, custom substrates, Microtiter plates |
| Biosensor functionalization (coating)Surface | – | – | – | – | Aptamers, Antibodies, Enzymes, Electrodes, optical sensor surfaces |
| Lab-on-a-Chip / microfluidics loadingAssembly | pL-µL accuracy | – | – | – | Reagents, Microchannels, Reaction wells |
| Assay miniaturizationTesting | – | – | – | – | Samples/reagents for diagnostics and drug screening |
| Spot detection / quality control with integrated head cameraTesting | – | – | – | – | – |
7 Anlagen & Maschinen
| Machine | Manufacturer / model | Quantity | Working area | Year built | Site |
|---|---|---|---|---|---|
| Benchtop microdispensing instrument | M2-Instruments iFOUR | – | Benchtop, for slides, membranes, chips, microtiter plates | – | Wildau, Germany |
| Piezo-Driven Microdispenser | M2-Instruments PDMD / PDMD-L | – | min. 20–30 pL, up to 1000 drops/s | – | – |
| Aspirate/Dispense Microdispenser | M2-Instruments M2MD AD | – | 10 nL to 5 µL, 3 interchangeable glass tips | – | – |
| Bulk-Reservoir Microdispenser | M2-Instruments M2MD BD | – | 20 mL glass vial, nL to low µL | – | – |
| Dummy PDMD (teaching accessory) | M2-Instruments Dummy PDMD | – | – | – | – |
| Wash station with droplet camera | M2-Instruments iFOUR wash station | – | – | – | – |
| Multi-channel microdispensing systems | M2-Automation | – | custom, scalable production | – | – |
Additional services
Reference customers
Quality
The iFOUR systems feature an integrated head camera for spot detection and quality control; the wash station with droplet camera supports droplet optimization via InDot software.
| Evidence | Wildau |
|---|---|
| Spot detection / quality control (head camera) | |
| ISO 9001 |
History
- 2019
Foundation of M2-Instruments GmbH in Wildau near Berlin