CDMO for custom synthesis and process development in fine chemistry at the Leverkusen and Dormagen sites.
Saltigo GmbH
Leverkusen · DormagenNew on Amplifa
About Saltigo
Saltigo GmbH is a contract development and manufacturing organization (CDMO) specialized in fine chemicals and a 100-percent subsidiary of LANXESS SE. The company develops and produces active ingredients and complex intermediates – from early process development through piloting and scale-up to industrial commercial production. The technology platform includes complex multi-step syntheses, high-pressure hydrogenation, metathesis and flow chemistry, phosgenation, halogenation, and numerous other specialized reaction techniques. Customers come from the crop protection, pharmaceutical, and specialty chemicals industries (including Advanced Materials, battery materials, catalysts, Consumer Care). Around 1,100 employees work in Leverkusen and Dormagen at CHEMPARK, one of the largest integrated chemical parks in Europe. In addition to custom manufacturing, Saltigo offers a portfolio of fine chemical intermediates as well as the insect repellent active ingredient Saltidin® (Icaridin).
- Site
- Leverkusen
- Processes
- Custom Manufacturing (contract synthesis, multi-step syntheses), Process development and piloting (Process Development and Pilot Production), Metathesis and flow chemistry (continuous process operation), High-pressure hydrogenation, Halogenation (chlorination, fluorination, bromination, iodination), Phosgenation, Electrophilic aromatic substitution & Friedel-Crafts chemistry (nitration, sulfonation,, Nucleophilic aromatic substitution & halogen exchange (Halex reaction)
- Materials
- Saltidin® (Icaridin/Picaridin), Custom Manufacturing (multi-step synthesis), Metathesis and Flow Chemistry, High-Pressure Hydrogenation, Halogenation, Phosgenation, Electrophilic Aromatic Substitution & Friedel-Crafts, Nucleophilic Aromatic Substitution & Halex
- Certificates
- ISO 9001:2015, ISO 14001, cGMP (partial)
- Founded
- 2005
- Employees
- 1100
- Industries
- Fine chemicals, Crop protection/Agrochemicals, Pharmaceuticals, Specialty chemicals, Specialty chemicals (Advanced Materials, battery materials, catalysts,
- 01
Process scouting and research
- 02
Process development and piloting
- 03
Scale-up
- 04
Custom manufacturing (contract synthesis)
- 05
Analytics and quality assurance
- 06
Regulatory services and product registration support
Technologies & Materials
Custom Manufacturing (multi-step synthesis)
Contract synthesis of complex organic intermediates and active ingredients from laboratory to industrial scale.
Metathesis and Flow Chemistry
Continuous process operation for the safe and efficient synthesis of organic chemicals.
High-Pressure Hydrogenation
Scalable hydrogenation and (de)hydrogenation of organic compounds.
Halogenation
Chlorination, fluorination, bromination, and iodination of organic substrates.
Phosgenation
Phosgenations backed by decades of operational experience and a proven safety philosophy.
Electrophilic Aromatic Substitution & Friedel-Crafts
Nitration, sulfonation, chlorosulfonation, alkylation, and acylation of aromatic compounds.
Nucleophilic Aromatic Substitution & Halex
Substitution and halogen-exchange reactions on activated aromatic substrates.
C–C Bond Formation & Couplings
Ullmann coupling, Grignard, Michael and aldol addition, ring closure, and the Simmons-Smith reaction.
Functional Group Transformation
Carbonylation, carboxylation, cyanation, amidation, (reductive) amination, sulfamidation, sulfation.
Alkoxylation Chemistry
Ethoxylation, oxyalkylation, and propoxylation of organic compounds.
Saltidin® (Icaridin)
Worldwide established active ingredient for insect repellents from own production.
Sites
Leverkusen
DERegistered office/headquarters and production
- Lot size
- a few kilograms (development) to several tonnes per batch
- Materials
- Fine chemicals, pharmaceutical intermediates, agrochemical active ingredients
- Process development laboratories
- Pilot plant
- Production facilities for multi-step synthesis
Dormagen
DEProduction site (CHEMPARK)
- Lot size
- a few kilograms (development) to several tonnes per batch
- Materials
- Fine chemicals, agrochemical intermediates, specialty chemicals
- Production facilities for custom manufacturing
Inside the production
Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| Custom Manufacturing (contract synthesis, multi-step syntheses)Engineering | – | – | a few kilograms (development – several tonnes per batch (commercial | – | Fine chemicals, Pharmaceutical intermediates, Regulatory Starting Materials (RSMs), Agrochemical intermediates and crop protection active, Specialty chemicals (Advanced Materials, |
| Process development and piloting (Process Development and Pilot Production)Engineering | – | – | – | – | – |
| Metathesis and flow chemistry (continuous process operation)Engineering | – | – | – | – | Organic chemicals |
| High-pressure hydrogenationEngineering | – | – | – | – | Organic chemicals |
| Halogenation (chlorination, fluorination, bromination, iodination)Engineering | – | – | – | – | Organic chemicals |
| PhosgenationEngineering | – | – | – | – | Organic chemicals |
| Electrophilic aromatic substitution & Friedel-Crafts chemistry (nitration, sulfonation,Engineering | – | – | – | – | Aromatic compounds |
| Nucleophilic aromatic substitution & halogen exchange (Halex reaction)Engineering | – | – | – | – | Activated aromatic substrates |
| C–C bond formation, couplings & ring construction (Ullmann coupling, Grignard, Michael addition,Engineering | – | – | – | – | Organic chemicals |
| Functional group transformation & derivatization (carbonylation, carboxylation, cyanation,Engineering | – | – | – | – | Organic chemicals |
| Oxidation, reduction & (de)hydrogenation (epoxidation, dehydrogenation, dehydration, hydrogenation)Engineering | – | – | – | – | Organic chemicals |
| Addition, elimination & alkoxylation chemistry (ethoxylation, oxyalkylation, propoxylation)Engineering | – | – | – | – | Organic chemicals |
| Rearrangement & specialty reactions (Beckmann, Bamberger & pinacol rearrangement, HofmannEngineering | – | – | – | – | Organic chemicals |
| Analytical services / comprehensive analyticsTesting | – | – | – | – | – |
| Project management and regulatory services (registration support)Engineering | – | – | – | – | – |
Additional services
Quality & Certification
Production is carried out applying ISO 9001, ISO 14001, and in part cGMP; comprehensive analytical services accompany all process stages. Saltigo is certified to ISO 9001:2015 (DQS, certificate 004312 QM15).
| Evidence | Leverkusen | Dormagen |
|---|---|---|
| ISO 9001:2015 | ||
| ISO 14001 | ||
| cGMP (partial) |
Company History
- 2005
Renaming of Dritte LXS GmbH to Saltigo GmbH on September 7, 2005.
- 2006
Spin-off of Saltigo GmbH as an independent company on March 29, 2006; 100% subsidiary of LANXESS.
- 2024
Michael Schäfer takes over the management of Saltigo effective February 1, 2024.