
Listed corporate group for medical cannabis and industrial hemp along the entire value chain.

SYNBIOTIC SE
Düsseldorf · Melz · Varaždin (HR)New on Amplifa
About SYNBIOTIC SE
SYNBIOTIC SE is a publicly listed (Xetra: SBX.DE) Societas Europaea headquartered in Düsseldorf and pursues a Europe-focused buy-and-build strategy in the medical cannabis and industrial hemp sector. The group integrates the entire value chain from cultivation through research and development and production to distribution and trade – from field to shelf. The subsidiaries cover organic hemp cultivation (Hanf Farm GmbH, Melz), production of cannabinoid extracts and CBD isolates (Ilesol Pharmaceuticals, Varaždin, 3,400 m² of production space), microbiological decontamination of cannabis raw materials (GOC NEXUS), wholesale and distribution (SynBiotic Distribution, SynBiotic Sales, MH medical hemp) as well as hemp foods and CBD cosmetics. Products include medical cannabis, dronabinol, full-spectrum extracts, CBD products, hemp foods and home-cultivation ranges with up to 4,000 items. A BMWK-funded project at Hanf Farm for AI-supported processing of biogenic raw materials (hemp, miscanthus) was funded with €1.6 million. Customers come from the pharmaceutical/pharmacy market, food, cosmetics and agriculture; distribution and partner networks exist, among others, in the Netherlands, Denmark, Spain, Portugal, Thailand and Canada.
- Site
- Düsseldorf
- Processes
- Hemp cultivation (industrial hemp and cannabis, organic hemp cultivation), Production of cannabinoid extracts and isolates (CBD isolates), Microbiological decontamination of cannabis GACP raw materials into EU-GMP pharmaceuticals, Production of hemp foods, Distribution/sale of medical cannabis, CBD products and hemp foods, Cultivation of industrial hemp and medical cannabis, Research & development (cannabinoids/terpenes), Production of cannabinoid extracts and CBD isolates
- Materials
- Hemp (industrial hemp/fibre hemp), Hemp protein, CBD (cannabidiol), Cannabis flowers / medical cannabis, Cannabinoid extracts, Dronabinol, Full-spectrum extracts, Terpenes
- Certificates
- EU-GMP decontamination, Supply chain quality management
- Industries
- Medical cannabis, Industrial hemp, CBD/cannabinoids, Pharma/pharmacy market, Food (dietary supplements), Cosmetics
- 01
Cultivation (industrial hemp/medical cannabis)
- 02
Research & development
- 03
Extraction and isolate production
- 04
Decontamination (GACP to EU-GMP)
- 05
Production of foods, cosmetics and dietary supplements
- 06
Import and wholesale
- 07
Sales and distribution
Raw Materials & Processes
Hemp (industrial hemp/fibre hemp)
Basic raw material for cultivation, foods, animal feed and fibre processing.
Cannabis flowers / medical cannabis
Raw material for therapeutic applications and the pharmacy market.
CBD (cannabidiol) / CBD isolates
Production of extracts and isolates in own production.
Cannabinoid extracts / full-spectrum extracts
Basis for pharmaceutical, dietary supplement and cosmetic products.
Terpenes
Component of cannabinoid- and terpene-containing solution approaches.
Hemp protein
Raw material for hemp foods.
Miscanthus / lignocellulosic fibre raw materials
Processing in AI-supported bio-economy production.
Locations

Düsseldorf
DEBusiness address/place of operation (Königsallee 19; Münsterstraße 336)
Melz
DEHanf Farm GmbH – organic hemp cultivation and organic raw material production
- Materials
- Hemp, miscanthus
- Planned AI-supported, fully automated factory for processing industrial hemp and lignocellulosic fibre raw materials
Varaždin
HRIlesol Pharmaceuticals – production of cannabinoid extracts/isolates
- Materials
- CBD, cannabinoid extracts
- Extraction and isolate production facility (3,400 m²)
Products


Inside the production


Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| Hemp cultivation (industrial hemp and cannabis, organic hemp cultivation)Agriculture/cultivation (not a classic manufacturing process) | – | – | – | – | Hemp, Cannabis |
| Production of cannabinoid extracts and isolates (CBD isolates)Extraction/refining (casting/machining not applicable) | – | – | – | – | Cannabinoid extracts, CBD isolates |
| Microbiological decontamination of cannabis GACP raw materials into EU-GMP pharmaceuticalsTesting/treatment (decontamination) | – | – | – | – | Cannabis |
| Production of hemp foodsFood production | – | – | – | – | Hemp, Hemp protein |
| Pharmaceutical/cosmetics production | – | – | – | – | Cannabinoid extracts, CBD, Terpenes |
| Bio-economy/fibre processing | – | – | – | – | Hemp, Miscanthus, lignocellulosic fibre raw materials |
| Distribution/sale of medical cannabis, CBD products and hemp foodsDistribution | – | – | – | – | Medical cannabis, CBD, Hemp products |
| Other (industrial hemp processing) | – | – | – | – | Hemp |
4 Anlagen & Maschinen
| Machine | Manufacturer / model | Quantity | Working area | Year built | Site |
|---|---|---|---|---|---|
| Cannabinoid extraction and isolate production facility (3,400 m² production space) | – | 1 | 3,400 m2 | – | Varaždin, Croatia |
| – | – | – | – | – | Melz, Germany (Hanf Farm) |
| – | – | – | – | – | GOC NEXUS OPERATIONS |
| Scientific cannabis breeding facility for developing new genetics | – | – | – | – | Denmark (WEECO Pharma) |
Additional services
Quality
SYNBIOTIC SE assures strict quality control across all production processes and the supply chain through majority shareholdings, including microbiological decontamination of GACP raw materials into EU-GMP pharmaceuticals.
| Evidence | Düsseldorf | Melz | Varaždin |
|---|---|---|---|
| EU-GMP decontamination | |||
| Supply chain quality management |
History
- 2014
Founding of GreenLight Pharmaceuticals Ltd. (Dublin)
- 2020
Stake in GreenLight Pharmaceuticals (25%); acquisition of Solidmind Nutrition GmbH (30.06.2020); first German listed cannabis corporate group
- 2021
Acquisition of GECA Pharma GmbH (Cologne, 100%); capital increase in kind to acquire Lean Labs Pharma GmbH; majority acquisition (50.1%) of Hanf Farm, Hemp Factory, Hempro International, MH medical hemp; Christian Angermayer/Apeiron approx. 45% largest shareholder; revenue forecast €15 million pro
- 2022
Launch of CBPlus and medical cannabis brand Hempamed Rx; canna.sales → SynBiotic Sales GmbH; GECA Pharma → SynBiotic Distribution GmbH
- 2023
Management change: Lars Müller hands over management to Daniel Kruse (29.09.2023)
- 2024
Partial cannabis legalization (01.04.2024); acquisitions of Bushdoctor, Ilesol Pharmaceuticals, WEECO Pharma, greensby, GOC NEXUS OPERATIONS; BMWK funding of €1.6 million for Hanf Farm; group revenue of >€20 million expected
- 2025
Bushdoctor GmbH files for insolvency (12.12.2025); increased international investor presence
- 2026
CANSOUL acquires strategic stake; Hempro International intends to initiate preliminary insolvency proceedings (Amtsgericht Münster)