Manufacturer of specialty and fine chemicals with contract synthesis from a few grams to 100 kg in Bitterfeld-Wolfen.
SYNTHON Chemicals GmbH & Co. KG
Bitterfeld-Wolfen (Chemical Park, Area A)New on Amplifa
About SYNTHON Chemicals
SYNTHON Chemicals GmbH & Co. KG is an owner-managed, ISO 9001 certified manufacturer of specialty and fine chemicals based in the Bitterfeld-Wolfen chemical park (Area A). The company produces liquid crystals, reactive mesogens and LC polymers for electro-optical displays, dyes and fluorescent dyes, materials for organic electronics, photoinitiators, heterocycles, crown ethers, calixarenes, isocyanides, metallocenes and pharmaceutical intermediates. In addition to its own product portfolio, SYNTHON offers contract syntheses and toll manufacturing in quantities from a few grams to about 100 kg – including synthesis development, process development with upscaling, purification, formulation, filling, analytics and raw material procurement. Production takes place in kilo laboratories and a pilot plant with multipurpose systems made of glass, enameled steel and Hastelloy (25–150 l, total reactor volume 600 l, -30 to +200 °C); yellow light laboratories enable the processing of UV-sensitive products. Customers include companies from electronics, pharmaceuticals, diagnostics, medical technology, dental, adhesives, display technology and security. The company has been based at the site since 1994 and has 2000 m² of usable space for production, laboratories, warehousing and offices.
- Site
- Bitterfeld-Wolfen
- Processes
- Contract synthesis / toll synthesis, Toll mixing / formulations / filling, Distillation / rectification, Preparative column chromatography (purification), Sublimation, Vacuum drying, Synthesis development / process development incl. upscaling, Process and reaction optimization
- Materials
- Liquid crystals, Reactive mesogens, LC polymers, Crown ethers, Calixarenes, Functional dyes / fluorescent dyes, Photoinitiators, Acrylates
- Certificates
- ISO 9001
- Founded
- 1994
- Industries
- Electronics (organic electronics, semiconductors), Display technology, Pharmaceuticals, Diagnostics, Medical technology / medical devices, Dental products
- 01
Product development
- 02
Synthesis and process development incl. upscaling
- 03
Contract synthesis / toll manufacturing
- 04
Purification (distillation, rectification, chromatography, sublimation)
- 05
Mixtures / formulations / filling
- 06
Quality control and analytics
- 07
Warehousing and logistics
Product Groups and Processes
Liquid crystals
Chemicals for electro-optical displays, also available in gram quantities via the webshop.
Reactive mesogens
For display technology and security applications.
LC polymers
Polymer cursors and precursors based on liquid crystal chemistry.
Charge transport materials (organic semiconductors)
Electron and hole transport materials for organic electronics and semiconductor devices.
Functional dyes and fluorescent dyes
Dyes for high-tech applications including intermediates.
Photoinitiators
UV-sensitive products, manufactured under yellow light conditions.
Acrylates and methacrylates
UV-sensitive monomers, produced in the yellow-light kilo laboratory.
Heterocycles
Intermediates for bioactive compounds.
Isocyanides
Specialty chemicals including for peptide synthesis.
Metallocenes
Organometallic compounds in the product portfolio.
Pharmaceutical intermediates
Intermediates for the pharmaceutical industry.
Crown ethers and calixarenes
Macrocycles as phase transfer catalysts and host compounds.
Site
Bitterfeld-Wolfen
DEHeadquarters: production, kilo laboratories, pilot plant, analytics, warehousing, offices (Chemical Park Area A)
- Part weight / size
- Quantity range from a few g to ca. 100 kg
- Lot size
- Gram range to 100 kg scale
- Materials
- Liquid crystals, reactive mesogens, dyes, photoinitiators, acrylates, heterocycles, pharmaceutical intermediates
- Multipurpose systems 150 l (enamelled) and 2 × 100 l (enamelled)
- Glass reactors (jacketed) 2 × 50 l, 2 × 30 l, 1 × 25 l
- 3 glass reactors 20 l
- Hastelloy reactor 30 l (1–3 bar)
- 30 l rectification unit (Hastelloy) with gas scrubber
- 6 l automatic distillation apparatus (Fischer)
- Rotary evaporators: 5 × 20 l (Heidolph), 2 × 10 l (Büchi)
- 12 thermostats -30 to +200 °C (Lauda, Haake, Julabo)
- 4 preparative chromatography columns (Ø 20/30 cm)
- Sublimation unit, vacuum dryer, Nutsche filters, filters, mills, mixers
- 3 filling stations (Denios fume hoods)
- Analytics: HPLC, GC, GC-MS, FT-IR, DSC, UV/VIS, polarimeter, viscometer
Products
Inside the production
Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| Contract synthesis / toll synthesisEngineering | – | – | a few g – 100 kg | – | organic compounds, heterocycles, dyes, liquid crystals, photoinitiators, pharmaceutical intermediates |
| Toll mixing / formulations / fillingEngineering | – | – | – | – | – |
| Distillation / rectificationEngineering | – | – | 30 l | – | – |
| Preparative column chromatography (purification)Engineering | – | – | – | – | – |
| SublimationEngineering | – | – | – | – | – |
| Vacuum dryingEngineering | – | – | – | – | – |
| Synthesis development / process development incl. upscalingEngineering | – | – | – | – | – |
| Process and reaction optimizationEngineering | – | – | – | – | – |
| Product developmentEngineering | – | – | – | – | – |
| Analytics and method development (HPLC, GC, GC-MS, FT-IR, DSC, UV/VIS, polarimetry, viscometry)Testing | – | – | – | – | organic compounds |
| Raw material procurement including incoming goods analyticsEngineering | – | – | – | – | – |
19 Anlagen & Maschinen
| Machine | Manufacturer / model | Quantity | Working area | Year built | Site |
|---|---|---|---|---|---|
| Multipurpose system (enamelled) | – | 1 | 150 l, -30 °C to +160 °C | – | Bitterfeld-Wolfen |
| Multipurpose system (enamelled) | – | 2 | 100 l, -30 °C to +160 °C | – | Bitterfeld-Wolfen |
| Glass reactor (jacketed) | – | 2 | 50 l, -20 °C to +200 °C | – | Bitterfeld-Wolfen |
| Glass reactor (jacketed) | – | 2 | 30 l, -20 °C to +200 °C | – | Bitterfeld-Wolfen |
| Glass reactor (jacketed) | – | 1 | 25 l, -20 °C to +200 °C | – | Bitterfeld-Wolfen |
| Glass reactor | – | 3 | 20 l, -20 °C to +150 °C | – | Bitterfeld-Wolfen |
| Hastelloy reactor | – | 1 | 30 l, -20 °C to +200 °C, 1–3 bar | – | Bitterfeld-Wolfen |
| Rotary evaporator | Heidolph | 5 | 20 l | – | Bitterfeld-Wolfen |
| Rotary evaporator | Büchi | 2 | 10 l | – | Bitterfeld-Wolfen |
| Distillation apparatus | Fischer | 1 | 6 l, automatic | – | Bitterfeld-Wolfen |
| Rectification unit | – | 1 | 30 l (Hastelloy) with gas scrubber; column with Sulzer packing or spinning band column with 100 | 2019/2020 | Bitterfeld-Wolfen |
| Thermostats | Lauda, Haake, Julabo | 12 | -30 to +200 °C | – | Bitterfeld-Wolfen |
| Preparative chromatography column | – | 2 | Diameter 20 cm, length 100 cm | – | Bitterfeld-Wolfen |
| Preparative chromatography column | – | 2 | Diameter 30 cm, length 100 cm | – | Bitterfeld-Wolfen |
| Sublimation unit | – | – | – | – | Bitterfeld-Wolfen |
| Vacuum dryer / dryer / Nutsche filters / filters / mills / mixers / absorbers | – | – | – | – | Bitterfeld-Wolfen |
| Filling station (Denios fume hoods) | Denios | 3 | Bottles up to 2.5 l or BULK goods | – | Bitterfeld-Wolfen |
| Analytical instruments (HPLC, GC, GC-MS, FT-IR, DSC, UV/VIS, polarimeter, viscometer) | – | – | – | 2018–2020 | Bitterfeld-Wolfen |
| Electronic laboratory notebook (Signals Notebook) | PerkinElmer Signals Notebook | – | – | 2022/2023 | Bitterfeld-Wolfen |
Additional services
Quality and Certification
SYNTHON is certified to ISO 9001 by TÜV Rheinland. Quality assurance covers the entire process from incoming goods inspection to product delivery with in-house analytics (HPLC, GC, GC-MS, FT-IR, DSC, UV/VIS and more), complete batch and inventory traceability, and the issuance of certificates of analysis according to customer methods.
| Evidence | Bitterfeld-Wolfen |
|---|---|
| ISO 9001 |
Company History
- 1994
Founded as SYNTHON AcMaRi Chemie GmbH & Co. KG in the Bitterfeld-Wolfen chemical park
- 1996
DKSH becomes exclusive representative for Japan; launch of the liquid crystals business line (know-how from MLU Halle-Wittenberg)
- 1997
Echo Chemical Co. Ltd begins marketing the products in Taiwan
- 2002
Renamed SYNTHON Chemicals GmbH & Co. KG; purchase of the company building and modernization of 1700 m² of usable space
- 2004
Acquisition of 10000 m² of building land for expansion
- 2006
Commissioning of a kilo laboratory (reactors 20–50 l) and a new filling station
- 2007/2008
Opening of the pilot plant with two 100-liter multipurpose systems
- 2008/2009
Research laboratory and new kilo laboratory with yellow light conditions (UV exclusion) in operation
- 2012
Start of cooperation with ASV innovative Chemie GmbH
- 2014
Takeover of the chemicals business of ASV innovative Chemie GmbH; usable space increased to 2000 m²
- 2015
Investment of 250,000 € in a new analytical laboratory and reconstruction of a large synthesis laboratory
- 2016
Expansion of the photoinitiator product line and transfer to yellow-light production
- 2017
Transfer of new medical devices into production
- 2018
Expansion of the analytical laboratory with GC and FTIR
- 2019/2020
Expansion with GC/MS; commissioning of a 150-l multipurpose system (enamelled) and a 30-l rectification unit (Hastelloy)
- 2021
Launch of the company's own webshop (liquid crystals, reactive mesogens, crown ethers, calixarenes) with quantities in the gram range
- 2022/2023
Introduction of the electronic laboratory notebook Signals Notebook (PerkinElmer)