Brokerage of contract manufacturing and custom synthesis in fine and specialty chemicals for the German-speaking market
Wirtz-Chemieprodukte GmbH
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About Wirtz-Chemieprodukte
Wirtz-Chemieprodukte GmbH was founded in 1980 by Heinz Wirtz and, as a family business now in its third generation, is a sales and project office for fine and specialty chemical products. The company brokers contract manufacturing and custom synthesis on the German-speaking market for its exclusive partner companies in Europe and the USA, acting not as a distributor: the business relationship exists directly between customer and principal, while Wirtz-Chemieprodukte acts as an external marketing and sales team as well as a local contact for technical and commercial questions. The brokered partner companies offer virtually the entire range of organic reactions, with multipurpose plants in stainless steel, Hastelloy and glass-lined steel in reactor sizes from laboratory scale up to 50 m³, pressure reactions in autoclaves up to 120 bar, as well as distillation, solvent recycling and analytical services. Projects are accompanied from laboratory sample through pilot production to industrial manufacturing on a multi-tonne scale, including reshoring and outsourcing projects. Customer industries include pharmaceuticals, crop protection, cosmetics, coatings, additives as well as forward-looking applications such as energy storage, natural-substance-based crop protection agents and bio-based plastics. All products come from Western manufacturing.
- Processes
- Custom syntheses and contract manufacturing (organic reactions, reactors from laboratory size to 50, Pressure reactions (autoclaves up to 120 bar, continuously up to 250 bar), Multi-stage syntheses, Small-volume production, Pilot production, Industrial manufacturing, Production under GMP, Process development, process optimization, synthesis optimization, feasibility studies
- Materials
- Stainless steel (plant material), Hastelloy (plant material), Glass-lined steel (plant material), Multipurpose plants, stainless steel, Multipurpose plants, Hastelloy, Multipurpose plants, glass-lined steel, Autoclave pressure reactions, Distillation and fractionation
- Certificates
- ISO 9001, ISO 14001, cGMP (pharmaceutical/veterinary), ISO 22716 / EFfCI (cosmetics), FSSC 22000 (food)
- Founded
- 1980
- Industries
- Pharmaceuticals, Crop protection, Cosmetics, Coatings, Additives, Energy storage
- 01
Project inquiry and market development in the German-speaking region
- 02
Brokering to a suitable partner company (contract manufacturing / custom
- 03
Process and synthesis optimization, feasibility studies
- 04
Laboratory samples and pilot production
- 05
Industrial manufacturing (multi-stage syntheses, GMP possible)
- 06
Distillative workup, recycling, analytics
- 07
Project support, troubleshooting and technical exchange
Processes and Plant Technology
Multipurpose plants, stainless steel
Standard system for organic reactions from laboratory to production scale.
Multipurpose plants, Hastelloy
For corrosive media and demanding synthesis conditions.
Multipurpose plants, glass-lined steel
For chlorinating and other corrosive reactions in fine chemistry.
Autoclave pressure reactions
Pressure reactions up to 120 bar, continuously up to 250 bar.
Distillation and fractionation
Distillation columns with up to 50 theoretical plates for workup.
Locations of the Partner Companies
Europe and USA (partner companies)
DEContract manufacturing and custom synthesis at brokered partner companies
- Part weight / size
- Multi-tonne scale
- Lot size
- Laboratory size to industrial production
- Materials
- Stainless steel, Hastelloy, glass-lined steel
- Multipurpose plants/reactors up to 50 m³ (usually 3–12 m³)
- Autoclaves up to 120 bar, continuously up to 250 bar
- Distillation columns up to 50 theoretical plates
- Thin-film evaporators
- Centrifuges
- Dryers (of various kinds)
Services
Inside the production
Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| Custom syntheses and contract manufacturing (organic reactions, reactors from laboratory size to 50Chemistry | – | – | Multi-tonne scale | – | organic chemicals |
| Pressure reactions (autoclaves up to 120 bar, continuously up to 250 bar)Chemistry | – | – | – | – | – |
| Multi-stage synthesesChemistry | – | – | – | – | – |
| Small-volume productionChemistry | – | – | – | – | – |
| Pilot productionChemistry | – | – | – | – | – |
| Industrial manufacturingChemistry | – | – | – | – | – |
| Production under GMPChemistry | – | – | – | – | – |
| Process development, process optimization, synthesis optimization, feasibility studiesChemistry | – | – | – | – | – |
| Transfer of batch processes to continuous processes / Continuous technologyChemistry | – | – | – | – | – |
| Distillations including fractionationChemistry | – | – | – | – | – |
| Solvent recyclingChemistry | – | – | – | – | – |
| Analytics / Analytical development / Analytical standards (synthesis and certification)Chemistry | – | – | – | – | – |
| Production and characterization of impuritiesChemistry | – | – | – | – | – |
| Acetal formation, acetylene chemistry, acetylation, aldol condensation, alcoholysis, alkylationChemistry | – | – | – | – | – |
| Benzoylation, biotransformation, boronic acid synthesis, bromination, bromonitromethane reactionsChemistry | – | – | – | – | – |
| Carbonylation, chlorination, chloromethane end-capping, chlorosulfonation, Claisen reactionsChemistry | – | – | – | – | – |
| Darzens synthesis, dealkylation, dehalogenation, dehydrogenations, diazomethane reactionsChemistry | – | – | – | – | – |
| Enzymatic reactions, epichlorohydrin chemistry, epoxidationsChemistry | – | – | – | – | – |
| Fluorine chemistry (aliphatic and aromatic), Friedel-Crafts acylation, Friedel-Crafts alkylationsChemistry | – | – | – | – | – |
| Gas-phase reactions, protected amino acids, Grignard reactions/Grignard reagentsChemistry | – | – | – | – | – |
| Halogenation, halogen exchange (Halex), heterocycle chemistry, Hofmann degradation, hydrazineChemistry | – | – | – | – | – |
| Iodination, isomerization, condensations, Leuckart reaction, maleinization, Mannich reactionChemistry | – | – | – | – | – |
| Sodium azide chemistry, nitration, nitromethane reactions, oligomerization, organometallic chemistryChemistry | – | – | – | – | – |
| Peptide chemistry, phase-transfer reactions, phosgenation, phosphorus oxychloride chemistryChemistry | – | – | – | – | – |
| Quaternization, redox reactions (sulfur), reductions, reductive aminationChemistry | – | – | – | – | – |
6 Anlagen & Maschinen
| Machine | Manufacturer / model | Quantity | Working area | Year built | Site |
|---|---|---|---|---|---|
| Multipurpose plants/reactors | – | – | Laboratory size to 50 m³ (usually 3–12 m³), stainless steel, Hastelloy, glass-lined steel | – | Europe and USA |
| Autoclaves for pressure reactions | – | – | up to 120 bar, continuously up to 250 bar | – | – |
| Distillation columns | – | – | up to 50 theoretical plates | – | – |
| Thin-film evaporators | – | – | – | – | – |
| Centrifuges | – | – | – | – | – |
| Dryers (of various kinds) | – | – | – | – | – |
Additional services
Quality and Certifications
All brokered partner companies hold ISO 9001 (quality) and ISO 14001 (environment) or operate according to ISO 9001. In addition, cGMP (pharmaceutical and veterinary), ISO 22716 or EFfCI (cosmetics), FSSC 22000 (food) as well as Kosher/Halal are possible; almost all represented companies have EcoVadis ratings.
| Evidence | Europe and USA (partner companies) |
|---|---|
| ISO 9001 | |
| ISO 14001 | |
| cGMP (pharmaceutical/veterinary) | |
| ISO 22716 / EFfCI (cosmetics) | |
| FSSC 22000 (food) |
History
- 1980
Founding of Wirtz-Chemieprodukte GmbH by Heinz Wirtz to represent medium-sized fine and specialty chemical producers from Western countries on the German-speaking market
Joining of chemist Oswald Wirtz (second generation); initial focus on the pharmaceutical and crop protection industries, later expansion of the portfolio to virtually all markets of the chemical industry
- 2021
Gerd Bucholski and Ann-Kathrin Wirtz take over the management; support of reshoring and outsourcing projects
- 2022
Oswald Wirtz leaves the company at the end of 2022; since then active in an advisory capacity