Development and manufacturing of NMR probes, microcoil detectors and sensor systems for liquid-phase NMR spectroscopy.
Voxalytic GmbH
KarlsruheNew on Amplifa
About Voxalytic
Voxalytic GmbH, based in Karlsruhe, develops and manufactures high-field NMR probes, microcoil NMR detectors and microcoil-based sensor solutions for liquid-phase NMR spectroscopy. Founded in 2014, the company is a spin-off of the Institute for Microsystem Technology (IMTEK) at the University of Freiburg and the Karlsruhe Institute of Technology (KIT). The portfolio includes flow probes, high-throughput probes for parallel measurements, electrochemistry probes for in-situ battery investigations, chirality probes as well as custom NMR probes and detectors. Production takes place in the cleanroom (microsystem technology) as well as with CNC precision milling, 3D printing of metals, ceramics and high-performance polymers, laser manufacturing and conventional mechanical production processes. Detector characterization is carried out using RF, optical, NMR and MRI measurement methods. Customers include, among others, the chemical industry, the NMR instruments industry and consumer electronics.
- Site
- Karlsruhe
- Processes
- Flow Probe (NMR flow probes with fluidic connections and flow cell), High-Throughput Probe (4x parallel heteronuclear NMR measurements with 1 spectrometer), Electrochemistry Probe (in-situ NMR experiments for charge/discharge cycles of pouch cell batteries), Chirality Probe (direct chiral differentiation without additives), Customized Probes (custom high-field NMR probes), Micro Coil NMR Detectors (microcoil NMR detectors for low- and high-field applications), Precise flow sensors (microcoil-based), CNC precision milling
- Materials
- Metals (for 3D printing and CNC milling), Ceramics (for 3D printing), High-performance polymers (for 3D printing), Metals, Ceramics, High-performance polymers
- Certificates
- Characterization using RF, optical, NMR and MRI measurement methods, FEM simulation for property prediction
- Industries
- Chemical industry, NMR instruments industry, Consumer electronics, Battery research
- 01
FEM simulation and circuit design
- 02
Cleanroom manufacturing of microcoil sensors (microsystem technology)
- 03
CNC precision milling, 3D printing, laser manufacturing and conventional
- 04
Characterization using RF, optical, NMR and MRI measurement methods
- 05
Assembly and adaptation to customer-specific applications
Materials and Processes
Metals
Used in 3D printing and CNC precision milling of probe components.
Ceramics
Processed by 3D printing for components of the NMR probes.
High-performance polymers
Plastics used in 3D printing for probe-specific components.
Sites
Karlsruhe
DEDevelopment, cleanroom manufacturing, precision mechanics and characterization
- Materials
- Metals, ceramics, high-performance polymers
- CNC precision milling
- 3D printing (metals, ceramics, high-performance polymers)
- Laser manufacturing
- Cleanroom technology
- RF, optical, NMR and MRI measurement methods
Products and Components
Inside the production
Industries
Processes & technical limits
| Processes | Tolerance | Max. part | Weight | Lot size | Materials |
|---|---|---|---|---|---|
| Flow Probe (NMR flow probes with fluidic connections and flow cell)Testing | – | – | – | – | – |
| High-Throughput Probe (4x parallel heteronuclear NMR measurements with 1 spectrometer)Testing | – | – | – | – | 1H/13C NMR detectors |
| Electrochemistry Probe (in-situ NMR experiments for charge/discharge cycles of pouch cell batteries)Testing | – | – | – | – | Proton NMR, Lithium NMR |
| Chirality Probe (direct chiral differentiation without additives)Testing | – | – | – | – | – |
| Customized Probes (custom high-field NMR probes)Engineering | – | – | – | – | – |
| Micro Coil NMR Detectors (microcoil NMR detectors for low- and high-field applications)Testing | – | – | – | – | – |
| Precise flow sensors (microcoil-based)Testing | – | – | – | – | – |
| CNC precision millingMachining | – | – | – | – | Metals, Ceramics, High-performance polymers |
| 3D printing (metals, ceramics, high-performance polymers)Additive | – | – | – | – | Metals, Ceramics, High-performance polymers |
| Laser manufacturingJoining | – | – | – | – | – |
| Conventional mechanical manufacturing technologiesMachining | – | – | – | – | – |
| FEM simulation and circuit designEngineering | – | – | – | – | – |
| Microsystem technology / microtechnology (cleanroom manufacturing of microcoil sensors)Engineering | – | – | – | – | – |
| Characterization of µ-NMR detectors (RF, optical, NMR and MRI measurement methods)Testing | – | – | – | – | – |
Quality and Characterization
Voxalytic characterizes its µ-NMR detectors and system solutions using state-of-the-art RF, optical, NMR and MRI measurement methods. Simulations based on more than three decades of experience enable precise prediction of properties such as line broadening, RF efficiency, gradient and temperature profiles.
| Evidence | Karlsruhe |
|---|---|
| Characterization using RF, optical, NMR and MRI measurement methods | |
| FEM simulation for property prediction |
History
- 2014
Foundation of Voxalytic GmbH by Jan Korvink, Ulrike Wallrabe and Jörg Funk as a spin-off of IMTEK (University of Freiburg) and KIT.
- 2025
Upgrade of a microcoil-based NMR probe system for electrochemistry to 100 W RF power; installation and test at the Helmholtz-Zentrum Berlin (proton and lithium NMR on pouch cell batteries).
- 2026
Grant of a European patent for the design of a chiral NMR detector; demonstrated 4-fold parallel high-resolution NMR spectroscopy with a single spectrometer (DOI: 10.1063/5.0326022).